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OCD: Psychological treatments

Psychotherapy involves face-to-face interactions with a therapist. It is seen as more personal than drug therapy and can be individualized to meet the needs of the client. Generally, psychotherapy is more focused on addressing a person's life situation and subjective understanding of his or her psychological problems.

There are two main approaches to the psychological treatment of OCD: Exposure Response Prevention (ERP) based and Cognitive Therapy (CT) that targets the dysfunctional beliefs that turn everyday intrusive thoughts into obsessions.

Exposure Response Prevention (ERP) 

ERP is based on the Behaviourist approach in psychology that suggests that our behaviours, both normal and abnormal, are learned. This means our behaviours are shaped by environmental experiences, as opposed to being hardwired by our genes. So, if behaviours are learned, this should mean that undesirable behaviours can be unlearned if the person is exposed to the "right" learning environment.

In the case of OCD, this process depends on the client being able to identify environmental cues that trigger obsessional thoughts. The therapist will help the person to do this, for example, by talking about certain places, people, and objects that may trigger their symptoms. These cues may also be automatic thoughts in response to physiological reactions; for example, aches and pains or a racing heart may trigger the cascade of obsessive thoughts. The therapist will also talk through the exact nature of the person’s obsessions and compulsions and how the two are related, including the person's fears about possible outcomes if compulsions are not carried out.

ATL: Critical thinking

The Coronavirus pandemic has had a significant effect on people living with OCD.  Before watching the video below, brainstorm how you think that people with OCD might be affected by the pandemic.

The video argues that the virus may have undermined OCD treatment.  Can you explain what is meant by this statement?

What suggestions does the video propose to help people with OCD during the pandemic?

 Teacher only box

The video argues that the virus may have undermined OCD treatment.  Can you explain what is meant by this statement?

A significant part of treatment is to realize that the world is not as threatening as one believes. The pandemic appears to contradict this advice.  Also, the pandemic reinforces many of the irrational beliefs of people with OCD - for example, the compulsion to clean one's hands and the need to do it perfectly in order to prevent harm to oneself or loved ones.

What suggestions does the video propose to help people with OCD during the pandemic?

One suggestion is to make sure that people with OCD are not socially isolated.  They need to interact with others, even if it is over Zoom. Friends need to make sure that they do things that help distract them from the pandemic so that they are not focused on the need to be clean or the uncertainty of the world. Friends should not check in to make sure that they are following all the necessary precautions - or discuss those that are not following the rules.  This will only make the situation worse.

ERP is similar to systematic desensitization, a therapy that is often used with people with phobias. Both ERP and systematic desensitization make use of fear hierarchies. The client and the therapist work together to rank different situations from the least anxiety-provoking to the most to create a hierarchy. The next step is for the ERP therapist to gradually expose their client to each situation in the hierarchy, starting with the least anxiety-provoking. Central to the success of ERP is the process of habituation, whereby stimuli that once were associated with distressing thoughts and anxiety become neutralized. This occurs through response prevention. During therapy, people are not allowed (prevented) to engage in their usual compulsions (responses), in order to neutralize their thoughts. Instead, they are forced to learn that intrusive thoughts can pass without becoming overwhelming and that their anxiety can, and will, dissipate in the absence of their usual compulsions. ERP also involves helping the person to generalize their new learning to other situations in their everyday lives, thus reinforcing the new learning and combatting relapse.

The following video outlines the therapy.

ATL: Critical thinking

Fear hierarchies are often used in the treatment of individuals with cleanliness compulsions. Very often the "level 1" task is something very simple - for example, touch a door handle in their own home without wiping it down. A level "10" would be using a public toilet. 

If you were going to fill in the other levels, what tasks would you give your client? Brainstorm the tasks and try to rank them from 2 - 9 before looking at the list of suggestions in the box below.

One example of a fear hierarchy included the following: get dressed without washing in between; touch the toilet door handle in your home; touch a shop door handle; touch a pedestrian crossing button, bring items home from the market without washing outside packaging, prepared food without washing hands repeatedly, tough a public toilet door handle.

ERP sometimes also involves imagining the most feared outcome, e.g. having to attend the funeral of a family member who died of salmonella due to their poor hand hygiene. This imaginal exposure (also called in vitro) helps the person to recognize that their thoughts bear no relation to actual events in the real world.

After the exposure and response prevention, the therapist and their client will discuss the experience, exploring how the reality was different from their initial expectations and what they have learned. Therapists often set homework tasks between sessions and the extent to which the client engages with these homework tasks often determines the rate of progress. Gradually, the client will work their way through the whole hierarchy supported by the therapist, who will conclude the treatment by creating a relapse prevention plan.

The whole program is usually completed with around 15 sessions, each lasting between 1.5 and 2 hours.

Evaluating ERP

There is a great deal of empirical support for ERP and it has been shown to be more effective than other therapies including relaxation therapy and anxiety management, (Hezel and Simpson 2013). It has also been shown to be effective across a wide range of treatment settings including inpatient and outpatients, as well as with people with varying severity of symptoms in a range of cultures.

In a meta-analysis by Eddy et al. (2004), ERP led to a clinically significant improvement for about 68.8% of participants who completed the program compared with 56.6% making a comparable level of improvement upon completion of cognitive therapy (CT). However, CT did have a higher recovery rate of 49.8% compared with 38.2% for ERP. Overall, ERP was deemed the most effective in reducing symptoms of the psychological therapies examined in this study. However, for those who were able to complete the cognitive therapy treatment, they were more likely to recover from the disorder.

Foa et al (2005) found that augmenting ERP with medication (e.g. clomipramine) did not improve its success rate, yet ERP plus medication was more effective than medication alone, providing further support for the role of ERP. Furthermore, Simpson et al. (2008, 2013) found ERP was more effective in increasing the effects of SSRIs than either stress management training or an additional drug, such as risperidone.

Despite the positive findings, around 35 - 40% of people with OCD do not recover completely after ERP; this is associated with poor compliance, lack of insight, (i.e. not recognizing that their thoughts or behaviours are irrational) and comorbid depression. 20 - 30% drop out of treatment because they find it time-consuming and/or too challenging.

Cognitive bias modification therapy (CBM)

Cognitive explanations of OCD focus on the idea that we all experience involuntary thoughts that intrude upon our conscious awareness but it is how we interpret and respond to them that sets apart people who develop OCD from those who do not. Psychologists such as Paul Salkovskis and Stanley Rachman have identified a number of cognitive biases common in people with OCD. For example, people with OCD tend to think of their intrusive thoughts as meaningful and generally negative, e.g. thinking about your father dying might be interpreted as a sign of being a bad person for imagining such an event.

Researchers have identified two different types of negative biases in people with OCD: attentional bias and interpretation bias. Attentional bias occurs when people selectively attend to negative stimuli and filter out positive stimuli, leading to an overestimation of the level of danger/threat. For example, a person may focus on negative news stories, e.g. Coronavirus death rates, as opposed to the positive new stories, e.g. communities coming together to help each other. Interpretation bias refers to the idea that people with OCD have a tendency to interpret ambiguous events in a negative light. If a person perceives the world as dangerous and full of possible threats, they will be more inclined to interpret events in a way that fits with this view. 

Cognitive bias modification aims to reduce the impact of these biases, thus easing a person's symptoms. CBM is generally a computer or mobile phone-based therapy where clients participate in training exercises. CBM-A tasks target attentional bias, shifting attention away from threatening/negative words, images, or faces towards non-threatening/positive stimuli. CBM-I tasks target interpretive biases; ambiguous stimuli are presented, such as words with missing letters and the person is trained to resolve the ambiguity in a positive way, (Derin and Yorulmaz 2020).

The following video explains how these tasks work in practice and how they have been ‘gamified’ for delivery via mobile phone applications. This exciting union of psychology and technology means evidence-based therapy is now accessible to anyone with a smartphone. This said, financial and geographical barriers still exclude many people, especially those in remote areas without network coverage or WIFI connections.

Evaluating CBM for OCD

 

Williams and Grisham (2013) conducted a laboratory experiment to assess the efficacy of CBM-I with people experiencing OCD symptoms. They found the technique useful in reducing interpretative bias, distress, and the urge to perform compulsions when placed in a situation designed to trigger symptoms associated with thought-action fusion. However, the study failed to show any impact on behavioural tasks tapping into core beliefs associated with perfectionism and the overestimation of threat. On a more positive note, the intervention was equally effective for people with both high and low scores on questionnaires (the DOCS) measuring the severity of their symptoms. It was unclear whether CBM would be effective for people with different types of OCD, i.e. cleaning, checking, order/symmetry, and forbidden thoughts as the researchers did not indicate the nature of their participants' symptoms. Finally, participants took part in only one session of CBM-I and results may have been more positive had the participants integrated regular CBM-I practice into their daily routines. 

Habedank et al (2017) examined the efficacy of CBM-A. Participants completed a minimum of 8 training sessions within four weeks and attentional bias was measured using a task called the dot-probe. Participants have to identify a letter that has previously appeared on their screen. A neutral image and one associated with OCD, e.g. a dirty cooker or sink appear just before the letter. Differences in reaction time to identify the letter indicate where the person tends to look - that is, at the neutral or OCD related stimuli. The CBM-A training sessions comprised dot-probe exercises where the letter always appeared on the same side of the screen as the neutral image, thus participants were primed to look at the neutral image as they knew this is where the letter would appear. In the placebo group, the position of the letter was randomized so participants did not learn to look at the neutral images. Following four weeks of therapy, the experimental group (n=58) showed a significant reduction in attentional bias compared with a placebo control group (n=50). Despite this improvement towards more positive bias, this did not transfer into a significant reduction in daily OCD symptoms. When followed up a month later, both groups self-reported equivalent reduction in symptoms, suggesting positive effects resulted from expectancy (a placebo effect) and were not a direct result of the CBM-A exercises.

Despite these seemingly negative findings, research suggests the CBM may be a helpful augmentation to ERP. Since ERP requires a highly trained practitioner, it is not a very accessible therapy for many people and self-conducted ERP (called sERP) has not had a high success rate. This said, research by Amir et al (2015) has demonstrated that when sERP is augmented with CBM-I it can have very positive outcomes. A sample of 22 people with OCD participated in a 7 week treatment programme and the researchers claim that with just one session with a trained ERP practitioner their participants showed symptoms reduction and functional improvement of a level comparable with ‘gold standard clinician-administered ERP’.  (Amir et al 2015).

Checking for understanding

Which of the following statements describes one of the assumptions upon which Exposure and Response Prevention (ERP) therapy is based?

Answer: ERP is based on the Behaviourist Approach in Psychology, which assumes that our individual differences are learned via environmental experiences and can therefore be unlearned. Behavioural psychologists believe that certain behaviours, e.g. checking or washing become repetitive as they have become associated with the removal of anxiety.

 

The first step of Exposure and Response Prevention (ERP) therapy is to:

Answer: An ERP therapist will first discuss triggers or cues that lead the person to feel distressed and start having obsessional thoughts, then they will develop a hierarchy to work through in the session, after each exposure session they will discuss the experiences and once the final stage of the hierarchy has been achieved, they will discuss a relapse prevention program.

 

Exposure and Response Prevention (ERP) therapy is similar to which other therapy?

Answer: ERP is similar to systematic desensitization in that they are both behavioural therapies that make use of fear hierarchies and gradual exposure to situations that trigger anxiety.

 

Habituation refers to the idea that the person in therapy learns that..

Answer: Habituation means the process of learning that a stimulus that once was associated with fear can be tolerated and that anxious feelings will subside; when a person has habituated to a certain stimulus it means it no longer triggers involuntary thoughts or emotions.

 

In Exposure and Response Prevention (ERP) therapy, people develop strategies to…

Answer: ERP is about facing the very situations that trigger anxiety rather than avoiding them but forcing oneself not to perform the compulsions that would usually be done in order to relieve that anxiety, i.e. the person must learn that the gradual subsidence of their anxiety is not contingent on them perform their rituals. With regard to the last option, sometimes the therapist will actually ask their client to think about unhappy events involving family members to help them to learn that their thoughts do not control events in the real world.

 

Which of the following statements is true about Exposure and Response Prevention (ERP) therapy?

Answer: Although more people make a clinical improvement using ERP than CBT, CBT is associated with a greater complete recovery rate. ERP is not a quick and easy solution; it takes several weeks/months and can be very challenging for people due to the need to face their fears. The use of drug treatments has not been shown to enhance its effects, although ERP has been shown to enhance the effects of medication.

 

Which of the following is true about Cognitive Bias Modification (CBM) therapy?

Answer: CBM has been shown to be effective in reducing biases that are believed to cause obsessional symptoms but the evidence does not suggest that CBM alone can reduce the symptoms themselves; this would require ERP. CBM has, on the other hand, been shown to be effective in improving the tolerance of ERP, thus helping people to stick with the full program and see their therapy through to the end. CBM can be delivered by mobile phone app, widening its accessibility but these apps are not necessarily free and remote locations may not have stable network or WIFI coverage.

 

Which of the following is not a limitation of Williams and Grisham’s (2013) study?

Answer: Williams and Grisham included people in their study who scored both low and high on the DOCs, a measure of obsessive-compulsive symptoms, but they were not actually diagnosed with OCD. The study needs to be replicated with a clinical sample in order to generalize the findings to people with OCD.

 

Which of the following is a similarity between the studies by Williams and Grisham (2013) and Habedank et al. (2017)?

Answer: Both WIlliams and Grisham (2013) and Habedank et al. (2017) showed that biases can be significantly reduced using CBM but neither clearly demonstrated a reduction in behavioural symptoms. Habedank et al. (2017) did include a follow-up although this was only one month later. Both studies had a control condition meaning the effects of the CBM training could be compared with changes in cognitive biases following a similar training exercise but without the intended modification element.

 

Which of the following is true?

Answer:  CBM_I has been shown to be an effective strategy to augment (enhance the efficacy) of self-conducted ERP. This was supported by the study by Amir et al. (2015). This study also suggested that CBM-A was not as effective at augmenting self-conducted ERP as CBM-I. The research by Foa et al. (2005) showed that ERP is not enhanced by medication. The research studies of Williams and Grisham (2013) and Habedank et al (2017) suggest CBM-I doesn't actually reduce behavioural symptoms of OCD and instead targets biases that are the cause of cognitive symptoms.

 

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