Signalling molecules are used to transfer information around the body. Once at the target cell, there are different ways in which different types of signalling molecule cause a response.
Which of the following is able to enter a cell directly through the phospholipid bilayer to cause a response without the requirement for a membrane protein?
Proteins in the cell surface membranes of mouse cells and human cells were labelled with coloured dyes, with a different colour for human and mouse proteins.
When a cell from each species is fused together, the different-coloured labels are first found in different regions of the hybrid cell’s cell surface membrane. After 40 minutes, the labels are evenly distributed around the entire cell surface membrane. This is shown in the diagram below; the viewpoint is looking down onto the surface of the membrane.
What explains this observation?
Groups of protein and phospholipid molecules in the cell surface membrane are attached to each other and move together.
Only protein molecules in the outer layer of the cell surface membrane can move freely between phospholipid molecules.
All protein molecules in the cell surface membrane are fixed to structures within the cell, but phospholipid molecules move freely between them.
Protein molecules in the outer layer of the cell surface membrane and those which span the bilayer can move freely between phospholipid molecules.