Blood clotting and heart disease.
Students sequence and explain the events of the chemical cascade which leads to the formation of a blood clot or scab using SOLO hexagons. This is followed by a short activity outlining an important application of this understanding, the causes and consequences of blood clot formation in coronary arteries.
Lesson Description
Guiding Questions
How does blood clot?
What have blood clots got to do with heart attacks?
Activity 1 - The chemical cascade of blood clotting
Using the SOLO hexagon cards on blood clotting below first match the images to the descriptions and then arrange them into an order which explains the process of blood clotting.
Activity 2 - What happens if blood clots form in coronary arteries?
Watch this video about what happens during a heart attack and answer the questions below.
Answer the worksheet of questions for the video "What happens during a heart attack"
This alternative video is also very good: What happens during a heart attack from Krishna Sudhir and Ted-Ed.
Activity 3 - Modeling the use of aspirin to prevent heart disease
This is a simple activity which illustrates how fat build up in an artery will slow blood flow and how the use of a chemical, like Aspirin, can remove the obstruction and restore the normal blood flow rate.
http://www.nuffieldfoundation.org/practical-biology/modelling-effect-aspirin-blood-clots
Teachers notes
The activities one this page are each free standing but cover some of the simple ideas about blood clotting and immunity. In total they should take about 1 hour, activity three is really shorter than the others.
The SOLO hexagons can be approached by different students in different ways. The simplest is to pair the images and the descriptions. Better students will be able to arrange the cards in a logical sequence. The best students will realise that there are a couple of different possibilities for a correct order.
Extra activity - video narration
Explain the process of blood clotting by narrating the Video prompts of blood clotting
Model answers for the blood clotting activity can be found on this teachers' page.
Model answers for the video questions can be found here:
Activity 3 is a nice little simulation but is rather easy for IB students.