Therapeutic Cloning Debate
Debate the issues in one of three ways
This lesson gives general guidance on ways of approaching a debate activity on therapeutic cloning. There is a curriculum connection with Cells (Cell Theory) and Genetics ( Biotechnology and Gene manipulation), although there is no reason to hold off the debate until a later unit if the teacher is prepared. Involving TOK, concepts in the debate may encourage students to use logic, reasoning and ways of knowing.
Guiding questions
What are the issues around the production and use of stem cells for therapeutic cloning?
Where do I stand in the decision about the ethical issues of using stem cells for therapeutic treatments?
Theory material
The domain of stem cell research is one of the fastest growing areas of biology today, so changes that happen now will not be expected of students in their exams. But the basics of outlining two uses of stem cells and a discussion of the ethical issues of therapeutic uses of stem cell cloning are necessary.
Some examples are: treatment of Parkinsons disease, Alzheimers disese, diabetes type 1, spinal cord damage.
Students should know
- the source of the stem cells
- the reason for using stem cells, ie. the disease or disorder
- where the stem cells are placed in the body
- what the stem cells should do
The Nobel prize in Medicine for 2012 was awarded to two scientists whose work has led to our understanding about stem cells. Here is the link to the Nobel prize in Medicine press release, which is quite readable by students. In 1962, John Gurdon did the experiment that now appears in most Biology textbooks. The transfer of the nucleus from an adult somatic cell into the enucleated egg cell that then develops into a full organism was the primary step in stem cell research. In 2006, Shinya Yamanaka, who was born around the time that Dr Gurdon published the first work, demonstrated that adult specialised cells can be induced into becoming pluripotent stem cells of iPSCs with the addition of a few genes.
One aspect of critical thinking is considering the source of the information one uses. Here are some links from a variety of sources that teachers can provide to students for their research on the topic.
International Society for Stem Cell Research - according to the website "The ISSCR is an independent, nonprofit organization formed in 2002 to foster the exchange of information on stem cell research."
Ethical issues fact sheet - from Euro Stem Cells, "unites more than 90 European stem cell and regenerative medicine research labs in a coordinated effort to engage with the public about our science." This article presents balanced arguments on many points which would be very useful for the debate activity below.
Bioethics - from the Oxford Journals, this article provides in depth theory and examples in the ethical discussion.
Life News - according to the website "LifeNews.com is an independent news agency devoted to reporting news that affects the pro-life community". This article has a very good representation of the ethical issue.
Students should continually remember their learning with international mindedness in light of the many different reserchers involved in this research and the complicated ethical issues argued between many different groups of people.
The attributes of the IB Learner profile, especially being risk-takers, reflective, caring, open-minded learners are in play as students grapple with these issues.
Critical Thinking Activities
Here are 4 ways to approach the ethical issues dilemma. The Ethical discussion worksheet is a worksheet which can be used to assist students to record their ideas before or during the discussions.
Where do I stand in the decision about the ethical issues of using stem cells for therapeutic treatments?
1. The "Cold" alternative
Prior to introducing the students to the topic, have the students make an initial stance. This deliberate asking the question "cold" will force them to think about what they have heard or read already. See the In Class activity below. Then allow the students to research more details and positions on the topic to establish their ideas by confirming or becoming educated if they were not sure.
2. The "Warm" alternative
After having introduced the topic and have had students do some research about the issues. This will allow students to prepare their arguments for the In Class activity below.
In Class
Have the students stand in the middle of the room.
Project or read out the question
"I think the production and use of stem cells poses more dangers than potential benefits."
Students should reflect on the question for about 1 minute, outlining their ideas. After this time, students should move to one side or other of the room.
Ask the students,
"Move to the left if you agree or move to the right if you disagree with the question."
"In small groups on your side of the room, discuss the reasons why you moved the way you did."
After about 1 minute of discussion, ask the students,
"You now have 2 minutes to decide among your group how to persuade or convince those students on the opposite side of the room to change their ideas to join your group. Consider the arguments they might propose and how you can make the counter argument."
Allow the teams to develop their arguments ( the 2 minutes is not really important but rather a stimulus to get to work and focus on the major ideas and not squabble about details).
Flip a coin to decide which team begins their persuasive arguments. Be sure to establish the rules of debate. Teachers need to be alert to prevent insults and bigotry about the issues.
"The rules that need to be followed to maintain an orderly discussion are:
- The first group presents all of their arguments in one presentation without interruption. The opposing group may make notes.
- The responding group will make their response by focussing on the arguments and facts presented and not on the personalities or opinions of those presenting.
- The responding group can present new arguments without interruption.
- The first group can then respond to the new arguments.
- Students are allowed to remain on their side or change sides.
- Students will then reflect on the facts, ideas and comments in the presentation.
3. The Debate
The 3rd way to approach the ethical issues is to set up a debate between shareholders in the issue.
How do I know the issues around the production and use of stem cells for therapeutic cloning?
How do students know where they stand on an issue? Setting up the debate between the interested parties invovled in ethical discussions will allow students to discover what they feel is right for themselves in the context of the other arguments.
Debate setting
For the ethical issues of therapeutic stem cell use, there are a number of different perspectives. Student can be allowed to select for themselves or be assigned by the teacher. Depending on the number of students, groups of various constituents can be created. Students in a group should research the perspective of that group on the issue to present the arguments and counter arguments. This way the students will have to look at the whole issue not just a biased viewpoint.
- Scientific / research community - why the research is important, benefits and potential risks.
- Religious community or communities - why the moral perspective is important.
- Legal community - what constitutes the legal rights in the local community.
- Medical community - how could the development help reduce or prevent suffering.
- Patient community - why is this research important to the individual who needs the treatment.
- Business community - what potential of employment and financial gain is involved.
- Other perspectives could be presented too.
The debate should follow strict rules so that shouting matches and disorder are avoided. Each group presents their perspective in short presentations, which could include prepared texts to be distributed.
In a random or predetermined order, responses are given by each group to specific arguments from the first round of presentations. This is why prepared texts would be advantageous.
Closure - students should write their reflections on the ideas presented to formulate their own positions.
4. Out of the comfort zone
One other way to present students to the issues in this ethical matter is to push them outside their own comfort zone. This might work well when the students already have a good idea of where they stand on the issue.
Where do I stand in the decision about the ethical issues of using stem cells for therapeutic treatments?
After the presentation of the various ethical issues in the class, students are asked to take a stand on the issue. Then students are to take up the opposite argument. So if a student were to decide that he was against the use of therapeutic stem cells, he would have to present the arguments in favour of using this technology.
Students need to consider how to convince someone else to accept the arguments that are counter to their own feelings or beliefs.
Flip a coin to decide which team begins their persuasive arguments. Be sure to establish the rules of debate. Teachers need to be alert to prevent insults and bigotry about the issues.
"The rules that need to be followed to maintain an orderly discussion are:
- The first group presents all of their arguments in one presentation without interruption. The opposing group may make notes.
- The responding group will make their response by focussing on the arguments and facts presented and not on the personalities or opinions of those presenting.
- The responding group can present new arguments without interruption.
- The first group can then respond to the new arguments.
- Students are allowed to remain on their side or change sides.
- Students will then reflect on the facts, ideas and comments in the presentation.
Student Activities
Ethical discussion worksheet - this worksheet can be given to the students prior to or near the end of the discussions to record their thoughts.
Students should summarise the major scientific points of the arguments to address the biology of the issue, including the examples of the therapeutic use of stem cells.
Students should reflect on the ethical arguments to evaluate where they stand on the issue after the discussions. The point is not to try to change someone's mind about the issue but to provide the information with which a student can use to determine his or her own stance.
Homework / assessments
Write the discussion points for the ethical issues of using human stem cells for therapeutic uses.