| Date | November 2017 | Marks available | 4 | Reference code | 17N.3.sl.TZ0.11 |
| Level | SL | Paper | 3 | Time zone | TZ0 |
| Command term | Explain | Question number | 11 | Adapted from | N/A |
Question
Enzyme activity depends on many factors. Explain how pH change causes loss of activity of an enzyme.
Markscheme
conformation/shape altered
OR
active site altered
OR
tertiary structure altered
acidic/basic/ionizable/COOH/carboxyl/NH2/amino groups in the R groups/side chains «react»
exchange/lose/gain protons/H+
ionic/H-bonds altered
Accept “substrate doesn't fit/fits poorly into active site” OR “enzyme denatures” for M1 but not “affects potential of
enzyme to form complex with substrate”.
Examiners report
[N/A]
Syllabus sections
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