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Date May 2010 Marks available 3 Reference code 10M.3.sl.TZ2.D1
Level SL Paper 3 Time zone TZ2
Command term State Question number D1 Adapted from N/A

Question

State the differences between the structures of morphine and diamorphine (heroin). State the names of all functional groups in the molecule of morphine.

Differences:

Functional groups:

Markscheme

Differences:

(two) hydroxy(l)/alcohol and phenol groups are esterified/replaced with ester/ethanoate/acet(yl)oxy groups / OWTTE;

Accept formulas instead of group names.

Functional groups:

hydroxy(l)/alcohol/phenol;

ether/oxa;

(tertiary) amine/amino;

double bond/alkene;

aromatic/benzene ring/phenyl/aryl;

Examiners report

Many candidates were able to identify the differences in the structures of morphine and diamorphine, but in the second part of the question quite a number of candidates gave the formula of the functional groups rather than their names, as required by the question.

Syllabus sections

Options » D: Medicinal chemistry » D.3 Opiates
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