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Date May 2010 Marks available 2 Reference code 10M.3.hl.TZ1.D1
Level HL Paper 3 Time zone TZ1
Command term Suggest Question number D1 Adapted from N/A

Question

Aspirin, paracetamol (acetaminophen), morphine and diamorphine (heroin) are all pain killers. Their structures are given in Table 20 of the Data Booklet.

Suggest a reagent that could be used to convert morphine into diamorphine and state the name of the type of reaction taking place.

Markscheme

ethanoic acid / ethanoic anhydride / ethanoyl chloride;

Accept formula instead of name.

diesterification / esterification / condensation;

Examiners report

Most could name the type of the reaction, and many did not name the reagent, with “carboxylic acid” being a common answer.

Syllabus sections

Options » D: Medicinal chemistry » D.3 Opiates
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