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Date May 2018 Marks available 2 Reference code 18M.3.sl.TZ2.15
Level SL Paper 3 Time zone TZ2
Command term Distinguish Question number 15 Adapted from N/A

Question

Drug testing is necessary to determine safe and effective doses.

Distinguish between the lethal dose (LD50) and the toxic dose (TD50).

Markscheme

LD50: amount/dose that kills 50% of the population

TD50: amount/dose that negatively affects/produces toxic effects in 50% of the population

 

Award [1 max] for “LD50 used in animal trials AND TD50 used in human studies”.

[2 marks]

Examiners report

[N/A]

Syllabus sections

Options » D: Medicinal chemistry » D.1 Pharmaceutical products and drug action
Options » D: Medicinal chemistry
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