| Date | November 2013 | Marks available | 1 | Reference code | 13N.3.sl.TZ0.12 |
| Level | SL | Paper | 3 | Time zone | TZ0 |
| Command term | Define | Question number | 12 | Adapted from | N/A |
Question
The therapeutic window is used as a measure of the safety of a drug. Define the term therapeutic window.
Markscheme
range of dosages/concentrations of drug able to treat disease successfully staying within safety limit/between therapeutic and toxic levels / OWTTE;
Accept LD50 over ED50.
Examiners report
This was answered well although few recognized the amide group in (a) (ii) and the therapeutic window was a little shaky. Many defined the therapeutic index which is not quite the same thing.
