List two consequences of anorexia nervosa.

1.

2.

Explain the causes, consequences and treatment of phenylketonuria (PKU).

Award [1] for any two consequences.

weight loss;

anemia;

depression/anxiety disorders;

abdominal distension;

hair loss/thinning;

flaky skin;

cessation of menstrual cycle / other hormonal imbalance;

death;

causes: genetic/inherited (homozygous recessive) disorder / mutation in (gene for) enzyme that converts phenylalanine into tyrosine / lack of phenylalanine hydrolase/PAH;

consequences: phenylalanine converted to phenylketone / mental retardation / brain damage / seizures;

treatment: low-phenylalanine diet / example of substances that cannot be eaten;

(eg any food containing protein / aspartame)

The answers to this question on consequences of anorexia nervosa were surprisingly vague and many were not able to give two good replies for the mark.

This question on phenylketonuria was either very well done, with many getting 2 or the full 3 marks, or not scoring any marks.