| Date | November 2018 | Marks available | 2 | Reference code | 18N.3.hl.TZ0.11 |
| Level | HL | Paper | 3 | Time zone | TZ0 |
| Command term | Explain | Question number | 11 | Adapted from | N/A |
Question
The transport of oxygen around the body is essential for life.
A graph showing saturation of oxygen against partial pressure of oxygen is shown.
Explain the shape of the graph from 0 to 50 % saturation.
Explain why carbon monoxide is very toxic and how it may be possible to treat carbon monoxide poisoning.
Markscheme
binding of oxygen/O2 «to one active site» affects shape of Hb/other active sites
OR
binding of one oxygen/O2 «molecule» affects binding of other oxygen/O2 «molecules» ✔
increasing affinity of Hb to oxygen/O2
OR
enhanced binding of «further» oxygen/O2 «molecules»
OR
cooperative binding ✔
Toxicity:
carboxyhemoglobin/Hb–CO does not readily dissociate
OR
CO + Hb Hb–CO AND forward reaction favoured
OR
affinity of carbon monoxide/CO for hemoglobin is «200 times/much» higher than that of oxygen/O2
OR
competitive inhibitor of oxygen/O2 binding ✔
Treatment:
moving patient to fresh air
OR
«in severe cases» inhaling pure oxygen/O2
OR
high pressure oxygen/O2 chamber ✔
Accept “move away from carbon monoxide/CO source” OR “remove carbon monoxide/CO source”.
Examiners report
Syllabus sections
-
18M.3.hl.TZ2.11a:
Hemoglobin’s oxygen dissociation curve is shown at a given temperature. Sketch the curve on the graph at a higher temperature.
- 17N.3.hl.TZ0.14b: Outline the change in oxidation state of the iron ions in heme groups that occurs when...
-
18M.3.hl.TZ1.10a:
Outline why anthocyanins are coloured.
-
17M.3.hl.TZ2.14a:
Explain the shape of the curve from 0 to X kPa.
-
17M.3.hl.TZ1.16a:
Explain the shape of the curve at low oxygen partial pressure up to about 5 kPa.
-
18M.3.hl.TZ2.11b:
Outline two differences between normal hemoglobin and foetal hemoglobin.
-
17M.3.hl.TZ2.14b:
Explain why carbon monoxide is toxic to humans.
-
19M.3.hl.TZ2.13a:
Outline why the complex formed between Fe2+ and oxygen is red. Refer to the diagram above and section 17 of the data booklet.
-
19M.3.hl.TZ1.19b(i):
Deduce the protons responsible for signals X and Y by marking them on the structure of aspirin in (a). Use section 27 of the data booklet.
- 19M.3.hl.TZ2.13b(ii): Sketch another line to show the effect of an increase in body temperature on the oxygen...
-
17N.3.hl.TZ0.14a:
State the half-equation for the reduction of molecular oxygen to water in acidic conditions.
-
17M.3.hl.TZ1.16b.ii:
Outline the effect of decreasing pH on the oxygen saturation of hemoglobin.
-
17M.3.hl.TZ1.16b.i:
Sketch a graph on the axes above to show the effect of decreasing pH on the binding of oxygen to hemoglobin (the Bohr Effect).
- 16N.3.hl.TZ0.16b: With reference to its chemical structure, outline whether this pigment is found in aqueous...
- 16N.3.hl.TZ0.16a: Outline why this molecule absorbs visible light.
-
16N.3.hl.TZ0.16c:
A student investigated the ability of anthocyanins to act as pH indicators. He extracted juice from blackberries and used a UV-vis spectrophotometer to produce absorption spectra at different pH values. His results are shown below.
Deduce the colour of the juice at each pH, giving your reasoning. Use section 17 of the data booklet.
- 19N.3.hl.TZ0.15a: Describe the function of chlorophyll in photosynthesis.
- 19N.3.hl.TZ0.14a: The graph shows the change in oxygen partial pressure in blood, measured at different pH...
-
19M.3.hl.TZ1.11b:
The absorption spectrum of chlorophyll a is shown below.
Suggest how the combination of chlorophyll a and carotenoids is beneficial for photosynthesis.
-
18M.3.hl.TZ1.10b:
Explain why the blue colour of a quinoidal base changes to the red colour of a flavylium cation as pH decreases.
-
19M.3.hl.TZ1.11a:
The absorption spectrum of β-carotene is shown below.
Explain its colour in terms of its absorption bands. Use section 17 of the data booklet.
-
19M.3.hl.TZ2.13b(i):
Explain the shape of the curve.
- 20N.3.hl.TZ0.6c(i): Proteins are polymers of amino acids. Sketch and label two oxygen dissociation curves, one...
-
19M.3.hl.TZ1.19b(ii):
Identify the splitting pattern of signals X and Y.
X:
Y:
-
20N.3.hl.TZ0.6c(ii):
Proteins are polymers of amino acids.
Explain why the affinity for oxygen of foetal hemoglobin differs from that of adult hemoglobin.
-
18N.3.hl.TZ0.11b:
Explain why carbon monoxide is very toxic and how it may be possible to treat carbon monoxide poisoning.
