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Date November 2013 Marks available 1 Reference code 13N.3.hl.TZ0.6
Level HL Paper 3 Time zone TZ0
Command term Identify Question number 6 Adapted from N/A

Question

Vitamins are organic micronutrients essential for good health. The structures of vitamins A, C and D are given in Table 21 of the Data Booklet.

Vitamin D is the only vitamin that can be synthesized in the body, by the action of sunlight on the skin.

Identify by name two functional groups that are common to all three of these vitamins.

[1]
a.

Only one of these three vitamins is soluble in water.

Identify this vitamin.

[1]
b.i.

Explain why this vitamin is soluble in water.

[2]
b.ii.

State one effect of vitamin D deficiency.

[1]
c.i.

Suggest why vitamin D deficiency diseases are becoming increasingly common in young people.

[1]
c.ii.

Markscheme

alcohol/hydroxyl group and alkene;

Accept carbon-carbon double bond.

Do not accept just double bond.

Do not accept hydroxide.

a.

vitamin C / ascorbic acid;

b.i.

several OH groups / polar molecule;

able to form hydrogen bonds with water;

b.ii.

softening/malfunctioning of bones / causes low/deficiency in calcium;

Accept rickets.

c.i.

less time outdoors / skin not exposed due to clothing/sunscreen / OWTTE;

Accept answers that show link with outdoors/sunlight.

c.ii.

Examiners report

Option B was a very popular, and question 6 was well answered with the exception of not listing alkenyl when identifying two functional groups common to three vitamins (A, C and D). Some students did not read the question on formula of zwitterion carefully and instead have the formula of the amino acid itself without any charges. In the separation of alanine and cysteine, the first mark was well scored by many while the second mark proved to be more demanding and often candidates lost this mark as no reference was made to charges or charges inversely stated. Although the disulfide bridge was correctly identified by even weaker candidates a much few were able to identify this as a covalent bond. Structure of the triglyceride was better answered than in past sessions but drawing the ester linkage correctly was still challenging for many candidates. Although the identification of the other reactant (water) was identified by many, the one essential condition (enzyme/lipase) was done poorly. Identification of the polyunsaturated fatty acid was done well by most but the second mark on its ability to lower LDL cholesterol was missed by most. The question on enzymes and inorganic catalysts was done poorly since comparison was often missing. While some candidates were able to suggest a pair of ions in cytochrome oxidase, only stronger candidates provided both pairs. Competitive and non-competitive inhibition was generally well done; however, the reason why it is more likely that NO, rather than the cyanide ion, acts competitively was not done as well. The redox reaction of the reducing agent \({\text{X}}{{\text{H}}_{\text{2}}}\) with \({{\text{O}}_{\text{2}}}\) produced a range of possible equations but rarely did candidates scored full marks.

a.

Option B was a very popular, and question 6 was well answered with the exception of not listing alkenyl when identifying two functional groups common to three vitamins (A, C and D). Some students did not read the question on formula of zwitterion carefully and instead have the formula of the amino acid itself without any charges. In the separation of alanine and cysteine, the first mark was well scored by many while the second mark proved to be more demanding and often candidates lost this mark as no reference was made to charges or charges inversely stated. Although the disulfide bridge was correctly identified by even weaker candidates a much few were able to identify this as a covalent bond. Structure of the triglyceride was better answered than in past sessions but drawing the ester linkage correctly was still challenging for many candidates. Although the identification of the other reactant (water) was identified by many, the one essential condition (enzyme/lipase) was done poorly. Identification of the polyunsaturated fatty acid was done well by most but the second mark on its ability to lower LDL cholesterol was missed by most. The question on enzymes and inorganic catalysts was done poorly since comparison was often missing. While some candidates were able to suggest a pair of ions in cytochrome oxidase, only stronger candidates provided both pairs. Competitive and non-competitive inhibition was generally well done; however, the reason why it is more likely that NO, rather than the cyanide ion, acts competitively was not done as well. The redox reaction of the reducing agent \({\text{X}}{{\text{H}}_{\text{2}}}\) with \({{\text{O}}_{\text{2}}}\) produced a range of possible equations but rarely did candidates scored full marks.

b.i.

Option B was a very popular, and question 6 was well answered with the exception of not listing alkenyl when identifying two functional groups common to three vitamins (A, C and D). Some students did not read the question on formula of zwitterion carefully and instead have the formula of the amino acid itself without any charges. In the separation of alanine and cysteine, the first mark was well scored by many while the second mark proved to be more demanding and often candidates lost this mark as no reference was made to charges or charges inversely stated. Although the disulfide bridge was correctly identified by even weaker candidates a much few were able to identify this as a covalent bond. Structure of the triglyceride was better answered than in past sessions but drawing the ester linkage correctly was still challenging for many candidates. Although the identification of the other reactant (water) was identified by many, the one essential condition (enzyme/lipase) was done poorly. Identification of the polyunsaturated fatty acid was done well by most but the second mark on its ability to lower LDL cholesterol was missed by most. The question on enzymes and inorganic catalysts was done poorly since comparison was often missing. While some candidates were able to suggest a pair of ions in cytochrome oxidase, only stronger candidates provided both pairs. Competitive and non-competitive inhibition was generally well done; however, the reason why it is more likely that NO, rather than the cyanide ion, acts competitively was not done as well. The redox reaction of the reducing agent \({\text{X}}{{\text{H}}_{\text{2}}}\) with \({{\text{O}}_{\text{2}}}\) produced a range of possible equations but rarely did candidates scored full marks.

b.ii.

Option B was a very popular, and question 6 was well answered with the exception of not listing alkenyl when identifying two functional groups common to three vitamins (A, C and D). Some students did not read the question on formula of zwitterion carefully and instead have the formula of the amino acid itself without any charges. In the separation of alanine and cysteine, the first mark was well scored by many while the second mark proved to be more demanding and often candidates lost this mark as no reference was made to charges or charges inversely stated. Although the disulfide bridge was correctly identified by even weaker candidates a much few were able to identify this as a covalent bond. Structure of the triglyceride was better answered than in past sessions but drawing the ester linkage correctly was still challenging for many candidates. Although the identification of the other reactant (water) was identified by many, the one essential condition (enzyme/lipase) was done poorly. Identification of the polyunsaturated fatty acid was done well by most but the second mark on its ability to lower LDL cholesterol was missed by most. The question on enzymes and inorganic catalysts was done poorly since comparison was often missing. While some candidates were able to suggest a pair of ions in cytochrome oxidase, only stronger candidates provided both pairs. Competitive and non-competitive inhibition was generally well done; however, the reason why it is more likely that NO, rather than the cyanide ion, acts competitively was not done as well. The redox reaction of the reducing agent \({\text{X}}{{\text{H}}_{\text{2}}}\) with \({{\text{O}}_{\text{2}}}\) produced a range of possible equations but rarely did candidates scored full marks.

c.i.

Option B was a very popular, and question 6 was well answered with the exception of not listing alkenyl when identifying two functional groups common to three vitamins (A, C and D). Some students did not read the question on formula of zwitterion carefully and instead have the formula of the amino acid itself without any charges. In the separation of alanine and cysteine, the first mark was well scored by many while the second mark proved to be more demanding and often candidates lost this mark as no reference was made to charges or charges inversely stated. Although the disulfide bridge was correctly identified by even weaker candidates a much few were able to identify this as a covalent bond. Structure of the triglyceride was better answered than in past sessions but drawing the ester linkage correctly was still challenging for many candidates. Although the identification of the other reactant (water) was identified by many, the one essential condition (enzyme/lipase) was done poorly. Identification of the polyunsaturated fatty acid was done well by most but the second mark on its ability to lower LDL cholesterol was missed by most. The question on enzymes and inorganic catalysts was done poorly since comparison was often missing. While some candidates were able to suggest a pair of ions in cytochrome oxidase, only stronger candidates provided both pairs. Competitive and non-competitive inhibition was generally well done; however, the reason why it is more likely that NO, rather than the cyanide ion, acts competitively was not done as well. The redox reaction of the reducing agent \({\text{X}}{{\text{H}}_{\text{2}}}\) with \({{\text{O}}_{\text{2}}}\) produced a range of possible equations but rarely did candidates scored full marks.

c.ii.

Syllabus sections

Options » B: Biochemistry » B.5 Vitamins
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