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Date May 2018 Marks available 2 Reference code 18M.3.sl.TZ2.18
Level SL Paper 3 Time zone TZ2
Command term Explain Question number 18 Adapted from N/A

Question

Excess acid in the stomach is often treated with calcium carbonate.

Formulate a chemical equation for the neutralization of stomach acid with calcium carbonate.

[1]
a.

Calculate the amount, in mol, of stomach acid neutralized by an antacid tablet containing 0.750 g calcium carbonate.

[1]
b.

Explain how omeprazole (Prilosec) regulates pH in the stomach.

[2]
c.

Markscheme

2HCl(aq) + CaCO3(s) → H2O(l) + CO2(g) + CaCl2(aq)

 

Accept ionic equation:

2H+(aq) + CO32–(aq) → CO2(g) + H2O(l)

[1 mark]

a.

«\(\frac{{0.750 \times 2}}{{100.09}}\) =» 0.0150 «mol HCl»

[1 mark]

b.

inhibits the secretion of stomach acid/H+

«active metabolites» bind «irreversibly» to «receptors of the» proton pump

 

Do not accept “hydrogen/H/H2” for “H+”.

Accept “PPI/proton pump inhibitor” for M2.

Accept “H+/K+ ATPase” for “proton pump”.

[2 marks]

c.

Examiners report

[N/A]
a.
[N/A]
b.
[N/A]
c.

Syllabus sections

Options » D: Medicinal chemistry » D.4 pH regulation of the stomach
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