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Date May 2018 Marks available 2 Reference code 18M.3.hl.TZ1.19
Level HL Paper 3 Time zone TZ1
Command term Outline Question number 19 Adapted from N/A

Question

Radiotherapy is one type of treatment for cancer.

Describe how ionizing radiation destroys cancer cells.

[2]
a.

Outline how Targeted Alpha Therapy (TAT) is used for treating cancers that have spread throughout the body.

[2]
b.

Markscheme

Any two of:

radiation causes breaks in DNA chains

OR

radiation causes errors in DNA sequences

 

«damage accumulates and» cells cannot multiply

rapidly dividing/cancer cells more susceptible

 

Accept “alters DNA”.

[2 marks]

a.

Any two of:

radiation source delivered directly to «targeted» cancer cells

by a carrier drug/protein/antibody

several sites in body can be targeted «at same time»

 

[2 marks]

b.

Examiners report

[N/A]
a.
[N/A]
b.

Syllabus sections

Options » D: Medicinal chemistry » D.8 Nuclear medicine (HL only)
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