| Date | November 2012 | Marks available | 3 | Reference code | 12N.3.SL.TZ0.15 |
| Level | Standard level | Paper | Paper 3 | Time zone | TZ0 |
| Command term | Explain | Question number | 15 | Adapted from | N/A |
Question
Explain the effects of tetrahydrocannabinol (THC) in terms of its action at synapses in the brain.
Markscheme
THC binds to cannabinoid receptor;
blocks release of (excitatory) neurotransmitter;
therefore it is inhibitory;
euphoria/anxiety/short-term memory loss/impaired coordination/pain relief;
extended use leading to social dysfunction/addiction;
Examiners report
Many candidates were able to gain 2 marks and the better ones 3 marks for the effects of THC in (b). Some responses, however, seemed to rely on common street knowledge rather than any biological knowledge.
Syllabus sections
Option A: Neurobiology and behaviour » Option A: Neurobiology and behaviour (Additional higher level topics) » A.5 Neuropharmacology
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