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Date November 2019 Marks available 1 Reference code 19N.3.hl.TZ0.13
Level HL Paper 3 Time zone TZ0
Command term List Question number 13 Adapted from N/A

Question

DNA, deoxyribonucleic acid, is made up of nucleotides.

List two components of nucleotides.

[1]
a.

Explain how the double-helical structure of DNA is stabilized once formed.

[2]
b.

Markscheme

Any two correct for [1]:
pentose «sugar»
OR
deoxyribose ✔

phosphate/phosphato «group»/residue of phosphoric acid ✔

NOTE: Accept “−OPO32−/−OPO3H/−OPO3H2” but not “PO43−”.

«organic» nitrogenous base
OR
nucleobase
OR
nucleic base
OR
purine
OR
pyrimidine ✔

NOTE: Accept the four bases together: “adenine/A, guanine/G, cytosine/C, thymine/T”.
Accept names or formulas.

a.

Any two of:
H-bonding between bases in each pair ✔
hydrophobic interactions/π-stacking between bases ✔
polar/charged/hydrophilic groups in sugar-phosphate backbone interactions with aqueous solution/water
OR
H-bonding AND ion-dipole interactions between phosphato «groups» andwater/histones ✔

Accept "phosphate groups are hydrophilic and form H-bonds with water".
Accept “H-bonding with histones”.

b.

Examiners report

[N/A]
a.
[N/A]
b.

Syllabus sections

Options » B: Biochemistry » B.8 Nucleic acids (HL only)
Options » B: Biochemistry
Options

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