The diagram shows part of a Taxol molecule in skeletal form.

Draw a circle around each chiral carbon.

Outline how chiral auxiliaries are used to synthesize the desired enantiomer.

Explain the process of solvent extraction by which Taxol is isolated.

Do not penalize any other notation (eg *) used for a circle.

chiral auxiliary creates stereochemical condition necessary to follow a certain pathway

OR

stereochemical induction

OR

existing chiral centre affects configuration of new chiral centres ✔

chiral molecule/auxiliary/optically active species is used/added/connected to the starting molecule «to force reaction to follow a certain path»

OR

«after new chiral centre created» chiral auxiliary removed «to obtain desired product» ✔

Any two of:

immiscible solvents ✔

partitioning of Taxol between the two solvents

Taxol more soluble in one solvent ✔

extraction carried out multiple times «to improve extraction» ✔

shaking/stirring the mixture ✔

separating the two layers ✔

evaporation of the solvent from the final solution «to obtain pure Taxol» ✔