DP Biology Questionbank
Option B: Biotechnology and bioinformatics (Additional higher level topics)
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Description
[N/A]Directly related questions
- 16N.3.HL.TZ0.11b: Discuss the implications of biopharming using a specific example.
- 16N.3.HL.TZ0.12d: Describe briefly how the cladogram was obtained.
- 16N.3.HL.TZ0.11a: Metabolites that indicate disease can be detected in urine. State a metabolite found in urine and...
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16N.3.HL.TZ0.12c:
(i) Identify the longest amino acid sequence where there are no differences amongst the five genera.
(ii) Suggest, with a reason, whether the DNA coding for the amino acid sequence identified in (c)(i) must be identical for the five genera.
- 16N.3.HL.TZ0.12e: Determine which two genera are most closely related according to their cytochrome c protein...
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16N.3.HL.TZ0.12b:
State the meaning of the dash (–) in the alignment.
- 16N.3.HL.TZ0.12a: State the bioinformatics tool used to obtain the alignment.
- 17M.2.HL.TZ1.1f.ii: Suggest a reason for the greater expression of the gene for the urea transporter after an...
- 17M.3.HL.TZ1.11a.i: Outline what is meant by the term genetic markers.
- 17M.3.SL.TZ1.16a: Calculate the diversity of site C. Working should be shown.
- 17M.3.HL.TZ1.11a.ii: Outline two uses of genetic markers.
- 17M.3.HL.TZ1.11b: Evaluate the use of viral vectors in gene therapy.
- 17M.3.HL.TZ1.11c: Outline the use of microarrays to test for genetic disease.
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17M.3.HL.TZ1.12:
Explain how BLAST searches are carried out and the applications of different types of these searches.
- 17M.3.HL.TZ1.9b: Explain what the branching off points represent in the cladogram of these fungi.
- 17M.3.HL.TZ2.12a: Outline one way in which genetic sequences can be used to indicate predisposition to a disease.
- 17M.3.HL.TZ2.12b: Outline the use of luminescent probes in the treatment of tumours.
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20N.3.HL.TZ0.14:
Explain how infection by a pathogen can be detected by the presence of its genetic material and of its proteins.
- 17N.3.HL.TZ0.10a: Identify the species that has the lowest percentage of coding sequences.
- 17N.3.HL.TZ0.10b: State how similar nucleotide sequences can be identified.
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17N.3.HL.TZ0.10c:
The yeast Saccharomyces cerevisiae was the first eukaryotic organism to have its entire genome sequenced. Suggest reasons for the choice of yeast as a study organism.
-
17N.3.HL.TZ0.10d:
Outline possible medical applications of the polymerase chain reaction (PCR).
-
17N.3.HL.TZ0.13:
Discuss biopharming.
- 18N.3.HL.TZ0.11e: BLASTp was used to obtain the alignment of the genes coding for PSY. Outline reasons for BLASTn...
- 18N.3.HL.TZ0.11b: Discuss whether production of Golden rice is an example of biopharming.
- 18N.3.HL.TZ0.11d: A bioinformatics analysis was performed on the protein PSY transcribed from the gene from corn...
-
18N.3.HL.TZ0.11f:
In the alignment there are dashes (–) in some positions. Deduce what is indicated by these dashes.
- 18N.3.HL.TZ0.12: Explain two or more laboratory tests that can be used to detect the presence of specific...
- 18N.3.SL.TZ0.10d: Describe how bioinformatics can help identify genes within the DNA of an organism.
-
18M.3.HL.TZ1.12b:
Describe how BLAST can be used to establish phylogenetic relationships between several organisms.
- 18M.3.HL.TZ2.12b: Regulations say that a protein is considered allergenic and unsafe for human consumption if at...
- 18M.3.HL.TZ2.12a.ii: Outline how the similar protein sequences were found.
-
18M.3.HL.TZ1.13:
Explain the process of gene therapy using viral vectors.
-
18M.3.HL.TZ1.12a:
Caenorhabditis elegans, a nematode, was the first multicellular organism whose genome was completely sequenced.
Outline the benefits of using model organisms for studying gene function.
- 18M.3.HL.TZ2.11a: Explain the reason that only cDNA from expressed genes binds to the DNA on the chip.
- 18M.3.HL.TZ2.11b: Explain how the information obtained in this microarray accounts for the differences between...
- 18M.3.HL.TZ2.12a.i: State a bioinformatic search tool that could be used to perform the alignment.
- 19M.3.HL.TZ1.13: Explain how antithrombin can be produced by biopharming.
- 19M.3.HL.TZ2.12a: Outline how a named vector is used to introduce a new gene into a plant.
- 19M.3.HL.TZ2.12b: State the role of marker genes.
- 19M.3.HL.TZ2.13: Discuss the use of microarrays in the diagnosis of disease.
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19N.3.HL.TZ0.12a:
Corn (Zea mays) is by far the most widely used biopharming plant, followed by soybeans, tobacco and rice. Around the world approximately 400 biopharming products are in open-air field trials.
State one possible application of biopharming.
-
19N.3.HL.TZ0.12c:
Outline the main principles of the Enzyme-Linked Immunosorbent Assays (ELISA) test.
- 19N.3.HL.TZ0.12b: Explain the use of a viral vector in gene therapy.
- 19N.3.HL.TZ0.13: Explain the use of DNA microarrays in genetic testing or diagnosis.
Sub sections and their related questions
B.4 Medicine
- 16N.3.HL.TZ0.11a: Metabolites that indicate disease can be detected in urine. State a metabolite found in urine and...
- 16N.3.HL.TZ0.11b: Discuss the implications of biopharming using a specific example.
- 17M.2.HL.TZ1.1f.ii: Suggest a reason for the greater expression of the gene for the urea transporter after an...
- 17M.3.SL.TZ1.16a: Calculate the diversity of site C. Working should be shown.
- 17M.3.HL.TZ1.11a.i: Outline what is meant by the term genetic markers.
- 17M.3.HL.TZ1.11a.ii: Outline two uses of genetic markers.
- 17M.3.HL.TZ1.11b: Evaluate the use of viral vectors in gene therapy.
- 17M.3.HL.TZ1.11c: Outline the use of microarrays to test for genetic disease.
- 17M.3.HL.TZ2.12a: Outline one way in which genetic sequences can be used to indicate predisposition to a disease.
- 17M.3.HL.TZ2.12b: Outline the use of luminescent probes in the treatment of tumours.
-
17N.3.HL.TZ0.10d:
Outline possible medical applications of the polymerase chain reaction (PCR).
-
17N.3.HL.TZ0.13:
Discuss biopharming.
-
18M.3.HL.TZ1.13:
Explain the process of gene therapy using viral vectors.
- 18M.3.HL.TZ2.11a: Explain the reason that only cDNA from expressed genes binds to the DNA on the chip.
- 18M.3.HL.TZ2.11b: Explain how the information obtained in this microarray accounts for the differences between...
- 18N.3.HL.TZ0.11b: Discuss whether production of Golden rice is an example of biopharming.
- 18N.3.HL.TZ0.12: Explain two or more laboratory tests that can be used to detect the presence of specific...
- 19M.3.HL.TZ1.13: Explain how antithrombin can be produced by biopharming.
- 19M.3.HL.TZ2.12a: Outline how a named vector is used to introduce a new gene into a plant.
- 19M.3.HL.TZ2.12b: State the role of marker genes.
- 19M.3.HL.TZ2.13: Discuss the use of microarrays in the diagnosis of disease.
-
19N.3.HL.TZ0.12a:
Corn (Zea mays) is by far the most widely used biopharming plant, followed by soybeans, tobacco and rice. Around the world approximately 400 biopharming products are in open-air field trials.
State one possible application of biopharming.
- 19N.3.HL.TZ0.12b: Explain the use of a viral vector in gene therapy.
-
19N.3.HL.TZ0.12c:
Outline the main principles of the Enzyme-Linked Immunosorbent Assays (ELISA) test.
- 19N.3.HL.TZ0.13: Explain the use of DNA microarrays in genetic testing or diagnosis.
-
20N.3.HL.TZ0.14:
Explain how infection by a pathogen can be detected by the presence of its genetic material and of its proteins.
B.5 Bioinformatics
- 16N.3.HL.TZ0.12a: State the bioinformatics tool used to obtain the alignment.
-
16N.3.HL.TZ0.12b:
State the meaning of the dash (–) in the alignment.
-
16N.3.HL.TZ0.12c:
(i) Identify the longest amino acid sequence where there are no differences amongst the five genera.
(ii) Suggest, with a reason, whether the DNA coding for the amino acid sequence identified in (c)(i) must be identical for the five genera.
- 16N.3.HL.TZ0.12d: Describe briefly how the cladogram was obtained.
- 16N.3.HL.TZ0.12e: Determine which two genera are most closely related according to their cytochrome c protein...
- 17M.2.HL.TZ1.1f.ii: Suggest a reason for the greater expression of the gene for the urea transporter after an...
- 17M.3.SL.TZ1.16a: Calculate the diversity of site C. Working should be shown.
- 17M.3.HL.TZ1.9b: Explain what the branching off points represent in the cladogram of these fungi.
-
17M.3.HL.TZ1.12:
Explain how BLAST searches are carried out and the applications of different types of these searches.
- 17N.3.HL.TZ0.10a: Identify the species that has the lowest percentage of coding sequences.
- 17N.3.HL.TZ0.10b: State how similar nucleotide sequences can be identified.
-
17N.3.HL.TZ0.10c:
The yeast Saccharomyces cerevisiae was the first eukaryotic organism to have its entire genome sequenced. Suggest reasons for the choice of yeast as a study organism.
-
18M.3.HL.TZ1.12a:
Caenorhabditis elegans, a nematode, was the first multicellular organism whose genome was completely sequenced.
Outline the benefits of using model organisms for studying gene function.
-
18M.3.HL.TZ1.12b:
Describe how BLAST can be used to establish phylogenetic relationships between several organisms.
- 18M.3.HL.TZ2.12a.i: State a bioinformatic search tool that could be used to perform the alignment.
- 18M.3.HL.TZ2.12a.ii: Outline how the similar protein sequences were found.
- 18M.3.HL.TZ2.12b: Regulations say that a protein is considered allergenic and unsafe for human consumption if at...
- 18N.3.SL.TZ0.10d: Describe how bioinformatics can help identify genes within the DNA of an organism.
- 18N.3.HL.TZ0.11d: A bioinformatics analysis was performed on the protein PSY transcribed from the gene from corn...
- 18N.3.HL.TZ0.11e: BLASTp was used to obtain the alignment of the genes coding for PSY. Outline reasons for BLASTn...
-
18N.3.HL.TZ0.11f:
In the alignment there are dashes (–) in some positions. Deduce what is indicated by these dashes.