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Date May 2011 Marks available 4 Reference code 11M.3.SL.TZ2.9
Level Standard level Paper Paper 3 Time zone Time zone 2
Command term Explain Question number 9 Adapted from N/A

Question

Explain the link reaction that occurs between glycolysis and the Krebs cycle.

Markscheme

pyruvate (from glycolysis) enters a mitochondrion;
enzymes in the matrix remove one carbon dioxide and hydrogen from the pyruvate;
hydrogen is accepted by NAD/forms NADH;
removal of hydrogen is oxidation;
removal of carbon dioxide is decarboxylation;
the whole process/link reaction is oxidative decarboxylation;
the product is an acetyl group which reacts with CoA/coenzyme A;
acetyl CoA enters Krebs cycle;
Accept any of the above points in the form of a clearly drawn and correctly labelled diagram.

Examiners report

In C3 many candidates discussed the Krebs cycle, rather than the link reaction as required. Careful reading of the question is vital.

Syllabus sections

Additional higher level » Topic 8: Metabolism, cell respiration and photosynthesis » 8.2 Cell respiration
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