The liver’s unique blood supply and system of ducts allow proper functioning of its hepatocytes and Kupffer cells. These cells are found throughout the liver in functional units called liver lobules. The image shows a cross section of the blood and bile paths in a liver lobule.

Label the structures I, II, III and IV.

Outline functions of hepatocytes that involve changing the chemical composition of the plasma.

I: Portal venule (Do not accept portal vein in place of venule)
II: Kupffer cell
III: «Hepatic» sinusoid
IV: Hepatocyte/hepatic cell

Award [1] for any two correctly labelled.

Can store or release glucose
OR
regulate nutrient levels

Can remove toxins from/detoxify blood

Produce plasma proteins

Synthesis of cholesterol/phospholipids/bile salts

(Do not accept functions of Kupffer cells (eg: breaking down red blood cells))

Discriminated well. Few candidates recognised structure I as a venule.

Discriminated well. The better candidates successfully outlined functions of hepatocytes.