To what extent did economic weakness lead to the fall of the Mamluks?

The question requires that candidates consider the extent to which economic weakness led to the fall of the Mamluks. Candidates may refer to economic issues such as the expansion of Portuguese trade in the Indian Ocean, a factor that strangled Mamluk commerce in the region, the financial mismanagement of the sultanate, and agricultural failures that weakened the economy and reduced government income. As a counter argument, candidates may refer to non-economic matters such as the effect of war against Tamerlane and internal rivalries in government. Candidates may stress the rising military power of the Ottoman Empire in the region, with the Ottoman–Mamluk War of 1515–16 being particularly significant in bringing about the final collapse of the sultanate.