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Date May 2010 Marks available 1 Reference code 10M.1.SL.TZ2.13
Level Standard level Paper Paper 1 Time zone Time zone 2
Command term State Question number 13 Adapted from N/A

Question

Which of the following is the cause of sickle-cell anemia?

A. Tryptophan is replaced by leucine.
B. Leucine is replaced by valine.
C. Glutamic acid is replaced by valine.
D. Lysine is replaced by glutamic acid.

Markscheme

C

Examiners report

This question turned out to be a good discriminator. Some teachers complained in the G2s that there was too much detail expected in this question. This exact statement is present however in the teacher notes of the guide.

Syllabus sections

Core » Topic 3: Genetics » 3.1 Genes
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