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Date November 2018 Marks available 3 Reference code 18N.3.HL:.tz0.16
Level Higher Level Paper Paper 3 Time zone time zone 0
Command term Explain Question number 16 Adapted from N/A

Question

Outline causes of hypoglycemia. 

[3]
a.

Explain the transportation of glucose across the cell membrance during physical activity.

[3]
b.

Markscheme

Several causes but most commonly:
high insulin levels among diabetics ✔

Can also exist in non-diabetics through:
insufficient food intake ✔

excessive exercise ✔

illness ✔

postponing or skipping a meal or snack ✔

drinking alcohol ✔

a.

glucose uptake into a cell is facilitated by the glucose transport proteins GLUT4 and GLUT1 ✔

GLUT4 transporters are stored inside intracellular vesicles that are translocated to cell membrane to allow greater glucose movement into cell ✔

GLUT4 transporters can be stimulated without insulin during physical exercise from other stimuli such as calcium ions ✔

glucose taken into muscle cells is quickly converted to glucose-6-phosphate to maintain glucose movement ✔

b.

Examiners report

[N/A]
a.

This question was answered well compared to May exam.

b.

Syllabus sections

Option D: Nutrition for sports, exercise and health » D.5. Glucose uptake (HL only) » D.5.3. Explain the transportation of glucose across the cell membrane when at rest and during physical activity.
Option D: Nutrition for sports, exercise and health » D.5. Glucose uptake (HL only)
Option D: Nutrition for sports, exercise and health

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