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Date May 2013 Marks available 2 Reference code 13M.3.HL.TZ1.13
Level Higher level Paper Paper 3 Time zone Time zone 1
Command term Distinguish Question number 13 Adapted from N/A

Question

Distinguish between the mode of action of steroid and peptide hormones.

[2]
a.

Outline the control of gastric juice secretion.

[2]
b.

Markscheme

a. peptide hormones do not enter the cell whereas steroid hormones do;
b. peptide hormones bind to a cell surface receptor whereas steroid hormones bind to a receptor in the cytoplasm;
c. peptide hormones act through a secondary messenger/cAMP whereas steroid hormones have (direct) effect on DNA;
d. steroid hormones have effect on gene transcription whereas peptide hormones change activities of cell/influence enzyme activity;

a.

a. involves both nerve impulses and the hormone gastrin;
b. sight/smell of food causes nerve impulses to be sent/reflex action;
c. food in stomach stimulates touch receptors/chemoreceptors/stretchreceptors releasing more gastric juice;
d. stretching of stomach wall stimulates secretion of the hormone gastrin;

b.

Examiners report

The better candidates were able to clearly distinguish between steroid and peptide hormones

a.

The control of gastric juice secretion by nerve impulses and the hormone gastrin was poorly done in general with few getting the 2 marks.  

b.

Syllabus sections

Option D: Human physiology » Option D: Human physiology (Additional higher level topics) » D.5 Hormones and metabolism
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